Center programs support its overall mission and the aims of faculty researchers. Our software programming team and Programs Director consult with faculty in the conceptualization, design, and implementation of digital health interventions. We also work closely with partners outside of academia to develop and test evidence-based digital health programs.

Current Programs

iOTA – the interactive Obesity Treatment Approach

iOTA combines the rigor of a personalized, evidence based weight loss approach with the ease of digital media. Developed in 2007 and tested in various populations, iOTA is an effective and highly scalable weight loss system. If you are interested in adapting and testing iOTA for your program or research study, please reach out!


Prompt is a software engine designed and developed to support behavior change research. Prompt allows for automated, personalized, interactive communication between participants and researchers via text message, interactive voice response (IVR), devices and apps with open APIs, and email. Here are a few examples of how we and our research partners have used Prompt:


Two-thirds of the United States (US) population is classified as obese or overweight. Novel methods are needed to improve weight loss in community settings. This NIH-funded pilot study is testing a weight loss intervention that uses MyFitnessPal to facilitate dietary self-monitoring and a cellular-connected body weight scale to facilitate regular self-weighing. Participants also receive bi-weekly group sessions for weight loss counseling and weekly text messages.

Principal Investigator: Corrine Voils, PhD

Partner Organizations: Duke School of Medicine, Duke School of Nursing, Duke Digital Health Identifier: NCT02691260


ICanSTEP: Increasing Physical Activity in Cancer Survivors Through a Text-messaging Exercise Motivation Program 

Cancer survivors have high cardiometabolic risk, partially due to cancer treatment itself. Increased physical activity can improve quality of life, ameliorate treatment-related side effects, reduce the risk of cancer recurrence, and extend overall survival. Despite these advantages, most cancer patients are sedentary. ICanSTEP is a 12-week pilot study funded by Duke’s Radiation Oncology department that aims to increase physical activity among cancer survivors. ICanSTEP participants wear a Fitbit Flex™ every day and daily step counts from Fitbit are sent to a software engine built by Duke Digital Health. Every morning, participants get a text message that tells them how many steps they walked the previous day, along with a feedback message about their progress and tips on how to increase their steps.

Principal Investigator: Bridget Koontz, MD

Partner Organizations: Duke Cancer Institute, Duke Digital Health Identifier: NCT02627079